Yinghong Sheng, Ph.D. Professor of Chemistry Department of Chemistry & Physics Office: Seidler Hall 302 Phone: 239-590-7636 Email: ysheng@fgcu.edu

An exciting and challenging aspect of computational chemistry is to develop inter-disciplinary projects that integrate state-of-the-art computational chemistry methods with biological, environmental, and material sciences.

My research experience includes study of (1) the structure-property relationships of nonlinear optical (NLO) materials and aromatic systems; (2) the reaction mechanisms of organic chemical reactions, homogeneous catalytic polymerization, cycloisomerization, dihydroxylation of olefins; (3) the molecular structures and the nature of interactions in weakly interacting systems; (4) photochromism; (5) Stimuli-Responsive Materials; (6) Chemical Sensors.

Computational Chemistry is a versatile and economical tool for different applications. It provides valuable data regarding the structure and interaction of molecules in different systems. The facility requirement for conducting computational studies is less demanding than setting up an experimental lab.

You can do your experiments on a PC cluster, or even on a single PC. It provides undergraduate or graduate students a platform to learn the fundamental computational methods and skills.

EDUCATION

Postdoctoral Fellow, Jackson State University
Postdoctoral Fellow, Emory University
Visiting Scholar, The Hong Kong University of Science & Technology, Hong Kong, China.
Ph.D., Nanjing University, Jiangsu, China
M.S., Beijing Normal University, Beijing, China
B.S., Jiangxi Normal University, Jiangxi, China

RESEARCH INTERESTS: Reaction Mechanism, Organic Chemistry, Organometallic Chemistry, Molecular Structures and Properties, Material Chemistry, Photochemistry, Biochemistry, Environmental Chemistry, Nonlinear Optical Material, Ionic liquids, Nitric Oxide Synthase.

Organic Chemistry and Organometallic Chemistry

· Mechanisms of organic reactions

· Design of new catalysts for stereoselective organic synthesis

· Early-transition-metal alkyl and alkylidene complexes; Design of new catalysts for olefin metathesis and acetylene polymerization

· Dihydroxylation of olefins by osmium tetraoxide

· Catalytic, endo-selective alkynol cycloisomerization, an important reaction type of the invention of new chemical transformations

Molecular Structures and Properties

· Molecular structures, properties, nature of chemical bonds in weakly interacting systems

· Molecular potential energy surfaces and vibrational spectra

· Material Chemistry and Photochemistry

· Nonlinear optical (NLO) property of conjugated organic molecules

· Photochromic materials

· Spectroscopic and theoretical determination on the structures of polymer films

Biochemistry

· The formation of glycosidic bonds between ribose and free pyrimidines – Prebiotic synthesis of pyrimidine nucleosides

· Mechanisms of reactions in biosystems

· Structural basis for regulation of electron transfer in Nitric-oxide Synthase (NOS)

· QSAR study on light-induced cytotoxicity of 16 polycyclic aromatic hydrocarbons on the US EPA priority pollutant list in human skin HaCaT keratinocytes

Environmental Chemistry

· Computational predictions and validation of properties, interactions and mechanisms of sorption of hydrophobic compounds

· Hydrogen sulfide and other contaminants sensing mechanisms

TEACHING

· Computational Modeling (CHM4512)

· Principles of Physical Chemistry (CHM3400)

· Principles of Physical Chemistry Laboratory (CHM3400L)

· General Chemistry II Lecture (CHM1046, Scale-up)

· General Chemistry II w/Laboratory (CHM1046C)

· General Chemistry II Lecture (CHM1046)

· General Chemistry II Laboratory (CHM1046L)

· General Chemistry I Lecture (CHM1045, Scale-up)

· General Chemistry I Lecture w/Laboratory (CHM1045C, Scale up)

· Physical Chemistry for Life Sciences w/Laboratory (CHM3005C)

· Physical Chemistry II Lecture (CHM3411)

· Physical Chemistry Laboratory (CHM3410L)

· Systems of Physical Science w/laboratory (ISC1002C)

· Senior Project Research in Biotechnology (BSC4910C)

· Direct Independent Study/Research in Biotechnology (BSC4905)

· Direct Independent Study/Research in Chemistry (CHM4905)

· General Chemistry II Laboratory (CHML 142, Honors)

· General Chemistry I Lecture (CHEM 141)

AWARDS AND GRANTS

· Acquisition of High-Performance Computation Servers for Computational Research and Education at FGCU. 2019. PI. FGCU Scholarship-Research Venture Fund.

· FGCU Computational Center: Modeling and Simulations, 2019.

· Grant (in 10000 hours of computing time) from Center for Advanced Research Computing (CARC) at the University of New Mexico. 2014-2018.

· Center for Chemical Evolution, $20,320,615, 2010-2015. Jointly funded by National Science Foundation (NSF Grant No. CHE-1004570) and National Aeronautics and Space Administration.

· FGCU Multi-Disciplinary Research Initiative Award, 2013-2014.

· Junior Faculty Teaching Excellence Award, Florida Gulf Coast University, 2008-2009.

PUBLICATIONS, TALKS & PRESENTATIONS

I. Selected Articles published

(1) Arsalan Mirjafari, David Siegel, Rachel Burton, Joseph Muller, Matthew Regner, Yinghong Sheng, Gregory McManus, James MacDonald “From gene delivery agents to ionic liquids: The impacts of cation structure and anion identity on liquefaction”, Journal of Molecular Liquids, 2019, 276, 334-337.

(2) Yinghong Sheng, Matthew Regner “Role of Water Molecules and Counterion on HS^- Sensing Reaction Utilizing a Pyrylium Derivative: A Computational Study”, J. Phys. Chem. A, 2019, 123, 3334-3343. (Featured in Cover of the journal)

(3) Zack Schultz, Jamie C. Gaitor, Rachel D. Burton, Matthew Regner, Yinghong Sheng, Arsalan Mirjafari “Phosphorodithioate-functionalized ionic liquids: synthesis, physicochemical properties and palladium complexation studies” J. Mol. Liq. 2019, 276, 334-337.

(4) Jinghui Li, Huaya Zheng, Wei Wang, Yubin Miao, Yinghong sheng and Changjian Feng “Role of an isoform-specific residue at the calmodulin-heme (NO synthase) interface in the FMN – heme electron transfer” FEBS Letters 2018, 592, 2425-2431.

(5) Jamie C. Gaitor, Lauren M. Paul, Melissa M. Reardon, Taha Hmissa, Samuel Minkowicz, Matthew Regner, Yinghong Sheng, Scott F. Michael, Sharon Isern and Arsalan Mirjafari “Ionic liquids with thioether motifs as synthetic cationic lipids for gene delivery” Chem. Commun., 2017, 53, 8328. (Cover Article Candidate)

(6) S. Thigpen, S. T. Nestor, R. A. O’Brien, S. Minkowicz, Y. Sheng, J. H. Davis, Jr., K. N. West, A. Mirjafari, “Thioether-functionalized picolinium ionic liquids: synthesis, physical properties and computational studies”. New Journal of Chemistry, 2017, 41, 1625-1630.

(7) O'Brien, Richard A.; Zayas, Manuel Sanchez; Nestor, Stephen T.; Gaitor, Jamie C.; Paul, Lauren M.; Edhegard, Forrest A.; Minkowicz, Samuel; Sykora, Richard E.; Sheng, Yinghong; Michael, Scott F.; Isern, Sharon; Mirjafari, Arsalan, “Correction: Biomimetic design of protic lipidic ionic liquids with enhanced fluidity” New Journal of Chemistry 2016, 40, 8970.

(8) O'Brien, Richard A.; Zayas, Manuel Sanchez; Nestor, Stephen T.; Gaitor, Jamie C.; Paul, Lauran M.; Edhegard, Forrest A.; Minkowicz, Samuel; Sykora, Richard E.; Sheng, Yinghong; Michael, Scott F.; Isern, Sharon; Mirjafari, Arsalan, “Biomimetic design of protic lipidic ionic liquids with enhanced fluidity” New Journal of Chemistry 2016, 40, 7795 – 7803.

(9) O'Brien, Richard A.; Zayas, Manuel Sanchez; Nestor, Stephen T.; Gaitor, Jamie C.; Paul, Lauran M.; Edhegard, Forrest A.; Minkowicz, Samuel; Sykora, Richard E.; Sheng, Yinghong; Michael, Scott F.; Isern, Sharon; Mirjafari, Arsalan, “CCDC 1450654: Experimental Crystal Structure Determination”, Cambridge Crystallographic Data Centre, 2016.

(10) Manuel Sanchez Zayas, Jamie C. Gaitor, Stephen T. Nestor, Samuel Minkowicz, Yinghong Sheng and Arsalan Mirjafari, “Bifunctional hydrophobic ionic liquids: Facile synthesis by thiol-ene “click” chemistry” Green Chemistry, 2016, 18, 2443 – 2452.

(11) Yinghong Sheng, Linghao Zhong, Dahai Guo, Gavin Lau, Changjian Feng, “Insight into structural rearrangements and interdomain interactions related to electron transfer between flavin mononucleotide and heme in nitric oxide synthase: A molecular dynamics study” Journal of Inorganic Biochemistry 2015, 153, 186–196.

(12) Richard A. Braun, Joseph L. Bradfield, Codey B. Henderson, Niloufar Mobarrez, Yinghong Sheng, Richard A. O’Brien, Alexandra C. Stenson, James H. Davis Jr. and Arsalan Mirjafari, “Click chemistry mediated synthesis of bio-inspired phosphonyl-functionalized ionic liquids” Green Chem., 2015, 17, 1259-1268.

(13) Yinghong Sheng, Jerzy Leszczynski, “Thermal racemization of spiropyrans: implication of substituent and solvent effects revealed by computational study”, Struct. Chem. 2014, 25, 667-677.

(14) Yinghong Sheng*, Yi Ren, “Computational Study on a HS^– Sensing Reaction Utilizing a Pyrylium Derivative”, J. Phys. Chem. A, 2012, 116, 5420–5427.

(15) Zhe Quan, Christine Purser, Rodney C. Baker, Terry Dwyer, Rajesh Bhagat, Yinghong Sheng, Jerzy R. Leszczynski, “Determination of Derivatized Urea in Exhaled Breath Condensate by LC-MS”, Journal of Chromatographic Science, 2010, 48, 140.

(16) Yinghong Sheng*, Heather D. Bean, Irena Mamajanov, Nicholas V. Hud and Jerzy Leszczynski, “Comprehensive Investigation of the Energetics of Pyrimidine Nucleoside Formation in a Model Prebiotic Reaction”, J. Am. Chem. Soc. 2009, 131, 16088.

(17) Chao Deng, Xiao-Peng Wu, Xiao-Ming Sun, Yi Ren, Ying-Hong Sheng* “Neutral hydrolyses of carbon disulfide: An ab initio study of water catalysis”, J. Comput. Chem. 2009, 30, 285.

(18) Min Yu, Marek. W. Urban, Yinghong Sheng, Jerzy, Leszczynski “Molecular Recognition at Methyl Methacrylate/n-Butyl Acrylate (MMA/nBA) Monomer Unit Boundaries of Phospholipids at p-MMA/nBA Copolymer Surfaces”, Langmuir, 2008, 24, 10382.

(19) Heather D. Bean, Yinghong Sheng, James P. Collins, Jerzy Leszczynski, and Nicholas V. Hud “Formation of a β-Pyrimidine Nucleoside by a Free Pyrimidine Base and Ribose in a Plausible Prebiotic Reaction”, J. Am. Chem. Soc. Communications. 2007, 129, 9556.

(20) Yinghong Sheng, Jerzy Leszczynski, Thuc-Quyen Nguyen, Anu Bamgbelu “Theoretical Study on the Structure and Property Relationship of the Cationic Conjugated Polyelectrolytes”, Structural Chemistry, 2007, 18, 827.

(21) Shuguang Wang, Yinghong Sheng, Manliang Feng, Lei Wang, Jerzy Leszczynski, Hiroyasu Tachikawa, and Hongtao Yu “Light-Induced Cytotoxicity of 16 Polycyclic Aromatic Hydrocarbons on the US EPA Priority Pollutant List in Human Skin HaCaT Keratinocytes: Relationship between Phototoxicity and Excited State Properties”, Environmental Toxicology, 2007, 22(3), 318-327.

(22) Yinghong Sheng, Jerzy Leszczynski “Theoretical Study of the Regioselectivity of the Cycloaddition Reaction between Cyclopentadiene and Methyleneketene”, Tetrahedron, 2006, 62(29), 7014.

(23) Yinghong Sheng, Szczepan Roszak, and Jerzy Leszczynski, “The Molecular Structures and Nature of Interactions in N₂H⁺-He_n (n = 1 - 12) Complexes”, Mol. Phys. 2005, 103, 1091.

(24) Zhe Quan; Yaru Song; Andrea Saulsberry; Yinghong Sheng; Yi-Ming Liu. “Capillary Electrophoresis for Diastereomers of (R,S)-Tetrahydroisoquinoline-3-Carboxylic Acid Derivatized with (R)-4-Nitro-7-(3-Aminopyrrolidin-1-yl)-2,1,3-Benzoxadiazole: Effect of Molecular Geometries.” Journal of Chromatographic Science, 2005, 43(3), 121-125.

(25) Zhe Quan, Yaru Song, Gladys Peters, Ming Shengwu, Yinghong Sheng, Huey-Min Hwang, and Yi-Ming Liu, “Chiral CE Separation of Dopamine Derived Neurotoxins”, Analytical Sciences, 2005, 21(2), 115-9.

(26) Yinghong Sheng, Szczepan Roszak, and Jerzy Leszczynski, “Microsolvation of N₂H⁺: The nature of interactions in N₂H⁺-(H₂)_n (n = 1 - 14) complexes”, J. Chem. Phys., 2004, 120, 4324.

(27) Yinghong Sheng, Yun-Dong Wu, Jerzy Leszczynski, "A Theoretical Study of the Ring-Opening of Metallacyclobutene Derived from the Addition of Acetylene to Molybdenum Alkylidenes", Organomatallics, 2004, 23, 3189.

(28) Yinghong Sheng, Jerzy A. Leszczynski, Antonio A. Garcia, Rohit Rosario, Devens Gust, Joseph Springer, “Comprehensive Theoretical Study of the Conversion Reactions of Spiropyrans: Substituent and Solvent Effects”, J. Phys. Chem. B, 2004, 108, 16233.

(29) Yinghong Sheng and Jerzy Leszczynski, “Theoretical Study of the Substituent and Solvent Effects on the Molecular Structures, Absorption and Emission Spectra of Spiropyrans” Collection of Czechoslovak Chemical Communications, 2004, 69, 47-62.

(30) Yinghong Sheng, Ramaiyer Venkatraman, Józef S. Kwiatkowski, Joanna Majewska and Jerzy Leszczynski, ^“A DFT and MP2 Study on the Molecular Structure, Vibrational Raman and Infrared Spectra of Halogenosubstituted Phosphoryl and Thiophosphoryl Compounds”, Structural Chemistry, 2003, 20, 511.

(31) Yinghong Sheng and Jerzy Leszczynski, “A Comprehensive Computational Study on OCH⁺-Rg (Rg = He, Ne, Ar, Kr, Xe ) Complexes”, Collection of Czechoslovak Chemical Communications, 2003, 68, 489.

(32) Yinghong Sheng, Djamaladdin G. Musaev, Frank, E. McDonald and Keiji Morokuma, “Computational Studies of Tungsten-Catalyzed endo-Selective Cycloisomerization of 4-Pentyn-1-ol”, J. Am. Chem. Soc., 2002, 124, 4149.

(33) Yinghong Sheng, Robert W. Gora, Malgorzata Kaczorowska, Szczepan Roszak, and Jerzy Leszczynski, “The molecular structures, energetics, and nature of interactions in Ar_n-N₂H⁺ (n=1-12) complexe”, J. Phys. Chem., 2002, 106, 11162.

(34) Yinghong Sheng and Jerzy Leszczynski, “A Comprehensive Computational Study of N2H+-X (X = He, Ne, Ar, Kr, Xe, and H₂) Complexes”, J. Phys. Chem., 2002, 106, 12095.

(35) Ying-Hong Sheng, Yun-Dong Wu, "Theoretical Studies on Acetylene Addition to Molybdenum Alkylidenes: The preference of a-and badditions", J. Am. Chem. Soc., 2001, 123, 6662.

(36) Ying-Hong Sheng, De-Cai Fang, Yun-Dong Wu, Xiao-Yuan Fu, Yuansheng Jiang, "DFT Study on the Mechanism of the Cycloaddition Reaction between Methyleneketene and 1-pyrroline-1-oxide", Journal Molecular Structure: THEOCHEM, 1999, 467, 31.

(37) Ying-Hong Sheng, De-Cai Fang, Yun-Dong Wu, Xiao-Yuan Fu, Yuansheng Jiang, "DFT Study on the Mechanism of the Cycloaddition Reaction between Methyleneketene and 5-Methylene-1,3-Dioxan-4,6-Dione: Solvent Effect and Regioselectivity", Journal Molecular Structure: THEOCHEM, 1999, 488, 187-194.

(38) Yinghong Sheng, Yuansheng Jiang, "Theoretical Study on Molecular First-Order Hyperpolarizability for Push-Pull Polyenes and Quinones: The Effects of Donor-Acceptor Pairs and Solvents", Bulletin of the Chemical society of Japan, 1999, 72, 2155.

(39) Yinghong Sheng, Yuansheng Jiang, Xiao-Chuan Wang, "An AM1 study of the relationship between the donor-acceptor strength and the polarizabilities of push-pull polyenes", J. Chem. Soc. Faraday Trans.,1998, 94, 47.

(40) Yinghong Sheng, Yuansheng Jiang, "AM1/CI Study on the First-Order Hyperpolarizability of Push-Pull Polyenes and Push-Pull Quinones. A Two-Level Model Evaluation", J. Chem. Soc. Faraday Trans., 1998, 94, 1823.

(41) Yinghong Sheng, Yuansheng Jiang, "Polarizability and Hyperpolarizability of Push-Pull Quinonoid Moleculaes: Simulation of Donor-Acceptor Pairs", J. Chem. Soc. Faraday Trans., 1998, 94, 1829.

(42) Yinghong Sheng, Decai Fang, Xiaoyuan Fu, "Theoretical Study on the Mechanism of the Cycloaddition Reactions between Methyleneketene and 5-methylene-1,3-dioxan-4,6-dione", Acta Physico-Chimica Sinica,1996, 12, 496.

(43) Yinghong Sheng, Decai Fang, Xiaoyuan Fu, "A Theoretical Study on the Mechanism of the Cycloaddition Reaction between Methyleneketene and 1-Oxo-Butadiene", Journal of Beijing Normal University (Natural Science), 1995, 31, 99.

(44) Yinghong Sheng, Decai Fang, Xiaoyuan Fu, The Seventh National Symposium on Physical Organic Chemistry of China. Pp201-202, Xi'an, Oct. 10-20, 1995.

(45) Book Chapter in Xin Xing Xue Ke Bai Wan Ge Wei Shen Me, Center National University, 1994.

II. Conference Talks & Presentations

(1) Mirjafari, Arsalan; O'Brien, Richard A.; Sykora, Richard; Sanchez Zayas, Manuel; Sheng, Yinghong, “Drug-based lipidic ionic liquids: A new class of biomaterials” 251st ACS National Meeting & Exposition, San Diego, CA, United States, March 13-17, 2016, Pages ORGN-638.

(2) Sanchez Zayas, Manuel; Gaitor, Jamie; Nestor, Stephen; Minkowicz, Shmuel; Sheng, Yinghong; Mirjafari, Arsalan “Click synthesis of bifunctional ionic liquids via thiol-ene chemistry for surface coating applications”, 251st ACS National Meeting & Exposition, San Diego, CA, United States, March 13-17, 2016, Pages ORGN-181.

(3) Shmuel Minkowicz, Yinghong Sheng, “Biomimetic Design of Lipidic Ionic Liquids with Enhanced "Fluidity" FGCU STEM Undergraduate Research & Internship Symposium, Dec. 4, 2015.

(4) Yinghong Sheng, Linghao Zhong, Jordan Wirth, “Computational simulations on structural changes and domain interactions between flavin mononucleotide and heme in murine inducible nitric oxide synthase” Drug Discovery & Therapy World Congress (DDTWC) at Boston, MA, June 22-25, 2015.

(5) Jonathan Voss, John Reilly, Yinghong Sheng, “Geometric and Electrostatic Changes in Histidine Ammonia-Lyase Active Site as Function of pH and Temperature” FGCU Research Day, April 17, 2015.

(6) Jordan Wirth, Yinghong Sheng, “Predicting the Docked structure of the Reductase and FMN/CaM Domains of Mammalian Inducible Nitric Oxide Synthase” FGCU Research Day, April 17, 2015.

(7) Yinghong Sheng, Linghao Zhong “Molecular Dynamic simulations on the redox-dependent conformational changes in interdomain electron transfer in Human inducible nitric oxide” Drug Discovery & Therapy World Congress (DDTWC) at Boston, MA, June 16-19, 2014.

(8) Matthew Smith and Jordan Wirth, Yinghong Sheng, “Computational Modeling on the Docking Structure between Flavin Mononucleotide-Calmodulin Complex and Oxygenase Domain in Human Inducible Nitric Oxide Synthase”, FGCU Research Day, April 18, 2014.

(9) Yinghong Sheng,* Linghao Zhong, Gavin Lau “Computational Simulations of the Intrinsic Regulation of Electron Transfer in Human Inducible Nitric Oxide Synthase” BIT’s 4th Annual Global Congress of Catalysis (GCC-2013) at the Dalian World Expo Center, Dalian, China during June 29 – July 1, 2013.

(10) Yinghong Sheng, “Computational Simulations of the Intrinsic Regulation of Electron Transfer in Human Inducible Nitric Oxide Synthase” Insitituet of Polymers, Jiangxi Provincial Key Laboratory of New Energy Chemistry, Nanchang University, China, June 24, 2013.

(11) Gavin Lau, Yinghong Sheng “Computational Modeling on the Docking Structure between Flavin Mononucleotide-Calmodulin Complex and Oxygenase Domain in Human Inducible Nitric Oxide Synthase”, FGCU Research Day, April 2013.

(12) Gavin Lau, Yinghong Sheng “Computational Modeling on the Docking Structure between Flavin Mononucleotide-Calmodulin Complex and Oxygenase Domain in Rat Neuronal Nitric Oxide Synthase”, FGCU Research Day, April 2013.

(13) Gavin Lau, Yinghong Sheng “Docking Structure between Human Inducible Nitric Oxide Synthase Oxygenase Domain (1NSI) and Reductase Domain (3HR4)”, Computational Modeling Sprout, Florida Gulf Coast University, December 2012.

(14) Yinghong Sheng, Linghao Zhong, Andrew Hedman “Development of New Force Field Parameters and Molecular Dynamic Modeling on Ribulose Nucleic Acids” Center for Chemical Evolution Center-wide Adobe Connect Meeting, May 3^rd, 2011.

(15) Irena Mamajanov, Heather D. Bean, Jerzy Leszczynski, Yinghong Sheng, Nicholas V. Hud “Experimental and Computational Investigations of Pyrimidine Nucleoside Formation in a Model Prebiotic Reaction” Astrobiology Science Conference 2010, 5676. 26-29 Apr 2010. League City, Texas. 

(16) Yinghong sheng “NAI Workshop without Walls: Molecular Paleontology and Resurrection: Rewinding the Tape of Life”. Web Conference, Nov. 8th, 2010.

(17) Yinghong Sheng “Introduction to Computational Chemistry and its Applications”, the 2010 Interdisciplinary Nanotoxicity Center Summer Institute, Jackson State University, July 21, 2010.

(18) Yinghong Sheng “The Application of Computational Chemistry in Some Prebiotic Reactions” Third Annual Meeting of Center for Chemical Evolution, Atlanta, GA, June 23-25, 2010.

(19) Yinghong Sheng “Comprehensive Investigation of the Energetics of Pyrimidine Nucleoside Formation in a Model Prebiotic Reaction”, the 238^th American Chemical Society National Meeting, Washington DC, August 14-21, 2009.

(20) Yinghong Sheng “Comprehensive Investigation of the Energetics of Pyrimidine Nucleoside Formation in a Model Prebiotic Reaction”, the 9^th Southern School on Computational Chemistry and Material Science, Jackson, MS, July 28-29, 2009.

(21) Marielys Figueroasierra, Yinghong Sheng, Jose Barreto “A Computational study on a HS^- Sensing Reaction which Utilizes a Pyrylium Derivative”, The 85th Annual American Chemical Society, Florida Section, Kissimmee, FL, United States, May 14-16, 2009.

(22) Marielys Figueroasierra, Yinghong sheng, “Theoretical Study on a New Chromo-chemodosimeter Selective for Sulfide Anion”, Research Day, Florida Gulf Coast University, April 24, 2009.

(23) Yinghong Sheng, Heather D. Bean, James P. Collins, Nicholas V. Hud, Jerzy Leszczynski, “A Comprehensive Investigation of Reactions between Ribose and the Free Pyrimidine Bases: Verification of Possibility of the Formation of Pyrimidine Nucleosides under Plausible Prebiotic Reaction Conditions”, pp26, pp29, International Symposium on Stimuli-Responsive Materials, Hattiesburg, Mississippi, October 28-29, 2008.

(24) Min Yu, Marek W. Urban, Yinghong Sheng, Jerzy Leszczynski, “Molecular Recognition at the Methyl Methacrylate/n-Butyl Acrylate (MMA/nBA) Monomer Unit Boundaries of Phospholipids at p-MMA/nBA Copolymer Surfaces” pp29, International Symposium on Stimuli-Responsive Materials, Hattiesburg, Mississippi, October 28-29, 2008.

(25) Min Yu, Marek W. Urban, Yinghong Sheng, Jerzy Leszczynski, “Phospholipids Molecular Recognition at the Monomer Boundaries of Copolymer Surfaces: Spectroscopic and Ab Initio Studies” 17^th International Conference on Current Trends in Computational Chemistry, pp176, Jackson, Mississippi, October 31-November 1, 2008.

(26) Yinghong Sheng “Theoretical Study on the Photochemistry of Spiropyrans”, University of Southern Mississippi, Hattiesburg, MS, February 5-6, 2007.

(27) Yinghong Sheng “Theoretical Study on the Photochemistry of Spiropyrans”, Texas Southern University, Houston, TX, May 17, 2006.

(28) Yinghong Sheng “Theoretical Study of the Photochemistry of Spiropyrans”, Texas A&M University-Kingsville, Kingsville, TX, April 9-10, 2006.

(29) Yinghong Sheng, Jerzy Leszczynski, “Theoretical Study of the Photochemistry of Spiropyrans” 6th Southern School on Computational Chemistry, pp99, Jackson, Mississippi, April 7-8, 2006.

(30) Yinghong Sheng “Theoretical Study of the Photochemistry of Spiropyrans”, Roosevelt University, Chicago, IL, February 20-23, 2006.

(31) Yinghong Sheng “Introduction to Computational Chemistry”, Roosevelt University, Chicago, IL, February 20-23, 2006.

(32) Yinghong Sheng, Jerzy Leszczynski, “Theoretical Study of the Photochemistry of Spiropyrans” 6th Southern School on Computational Chemistry, pp99, Jackson, Mississippi, April 7-8, 2006.

(33) Floyd A. Fayton Jr.^†, Yinghong Sheng, Jerzy Leszczynski, “Computational study on the mechanism of the cycloadition reaction between methyleneketene and cyclopetadiene” The Computational Center for Molecular Structure and Interactions (CCMSI) Summer Institute, Jackson, MS, June 5 – July 30, 2005. (^† Floyd A. Fayton Jr. won the Third Place Prize of the Student Presentation.)

(34) Jason Ford-Green^‡, Ayourinde Hassan, Yinghong Sheng, “DFT Study on the Reaction Mechanism of the 1,3-Dipolar Cycloaddition between Ethane and Nitrile Oxide”, 13^th International Conference on Current Trends in Computational Chemistry, pp53, Jackson, Mississippi, November 12-13, 2004. (^‡ Jason Ford-Green won the First Place Prize of the Best Student Poster.)

(35) Jason Ford-Green, Ayourinde Hassan, Yinghong Sheng, “DFT Study on 1,3-Dipolar Cycloaddition between Ethane and Nitrile Oxide”, 2004 Annual Biomedical Research Conference for Minority Students (ABRCMS), G35, Dallas, Texas, November 10 - 13, 2004.

(36) Jason Ford-Green, Ayourinde Hassan, Yinghong Sheng, “DFT Study on 1,3-Dipolar Cycloaddition between Ethane and Nitrile Oxide”, Computational Center for Molecular Structure and Interactions 2004 Summer Institute, pp6, Biloxi, Mississippi, July 29, 2004.

(37) Yinghong Sheng, Ray Butcher, Haijun Jiao, Bakhtiyor Rasulev, Jiande Gu, Jerome Karle, and Jerzy Leszczynski, “Novel Aromatic 7,8-Diazapentalenes” 4th Southern School on Computational Chemistry, pp105, Orange Beach, Alabama, March 26-27, 2004.

(38) Yinghong Sheng, Szczepan Roszak, and Jerzy Leszczynski, “The Molecular Structures and Nature of Interactions in N₂H⁺-X_n (X = He, Ne, n=1-17) Complexes” 3rd Southern School on Computational Chemistry, pp68, Orange Beach, Alabama, March 28-29, 2003.

(39) Demarcio Reed, Yinghong Sheng, and Jerzy Leszczynski, “Theoretical Study on Thermal Conversion of Benzopyran: Subsituent and Solvent Effects” 12^th International Conference on Current Trends in Computational Chemistry, pp149, Jackson, Mississippi, October 31- November 1, 2003.

(40) Yinghong Sheng, Ray Butcher, Bakhtiyor Rasulev, Jerome Karle, and Jerzy Leszczynski, 12^th International Conference on Current Trends in Computational Chemistry, pp160, Jackson, Mississippi, October 31- November 1, 2003.

(41) Latasha Salter, Yinghong Sheng and Jerzy Leszczynski, “A CASSCF Study on the Mechanism of C-O Cleacage in Pyran” Computational Center for Molecular Structure and Interactions 2002 Summer Institute, Orange Beach, Alabama, July 31, 2002.

(42) Yinghong Sheng and Jerzy Leszczynski, “Molecular Structures and Properties of N₂H⁺-X (X=He, Ne, Ar, Kr, Xe and H₂) Complexes”, Second Southern School on Computational Chemistry, pp63, Orange Beach, Alabama, March 22-23, 2002.

(43) Yinghong Sheng, Szczepan Roszak, and Jerzy Leszczynski, “The Molecular Structures and Nature of Interactions in N₂H⁺-Ne_n (n = 1 - 12) Complexes”, 11^th International Conference on Current Trends in Computational Chemistry,pp138, Jackson, Mississippi, November 1-2, 2002.

(44) Yinghong Sheng, Ramaiyer Venkatraman, Józef S. Kwiatkowski, Joanna Majewska and Jerzy Leszczynski, “Theoretical Study on the Molecular Structures and Vibrational Spectra of Halogenosubstituted Phosphoryl and Their Thio-analogs”, 11^th International Conference on Current Trends in Computational Chemistry,pp139, Jackson, Mississippi, November 1-2, 2002.

(45) Yinghong Sheng and Jerzy Leszczynski, “A Comprehensive Theoretical Study on the Reaction Mechanisms of the Inversion Reaction Between Spiropyrans and Merocyanines and the Racemization of Spiropyrans”, 11^th International Conference on Current Trends in Computational Chemistry, pp140, Jackson, Mississippi, November 1-2, 2002.

(46) Yinghong Sheng; Djamaladdin G. Musaev,; Subba K. Reddy; Frank E. McDonald; Keiji Morokuma,  “Theoretical studies of tungsten catalytized endo- and exo-selective cyclization of 1-alkyn-5-ol”.  Abstracts of Papers, 222nd ACS National Meeting, Chicago, IL, United States, August 26-30, 2001.

(47) Yinghong Sheng, Robert W. Gora, Malgorzata Kaczorowska, Szczepan Roszak,and Jerzy Leszczynski, “The Molecular Structures and Nature of Interactions in N₂H⁺-Arn (n = 1 - 12) Complexes”, 10^th International Conference on Current Trends in Computational Chemistry, pp210, Jackson, Mississippi, November 1-3, 2001.

(48) Yinghong Sheng, Szczepan Roszak, and Jerzy Leszczynski, “The Molecular Structures and Nature of Interactions inN₂H⁺-(H₂)_n (n = 1 - 12) Complexes”, 10^th International Conference on Current Trends in Computational Chemistry, pp211, Jackson, Mississippi, November 1-3, 2001.

(49) Ying-Hong Sheng, and Yun-Dong Wu, “Theoretical Studies on Acetylene Addition to Molybdenum alkylidenes: The Preference of alpha- and beta-Additions”, Workshop on Computational Chemistry, Hong Kong, Feb 21-23, 2000.

(50) Yun-Dong Wu and Ying-Hong Sheng, “Theoretical Studies on Ring-Opening of Metallacyclobutenes Derived from Acetylene Addition to Molybdenum Alkylidenes”, Workshop on Computational Chemistry, Hong Kong, Feb 21-23, 2000.

(51) Yun-Dong Wu and Ying-Hong Sheng, “Is a diradical Mechanism Possible for Amine Accelerated Dihydroxylation by Oxmium Tetraoxide? A theoretical Study”, Workshop on Computational Chemistry, Hong Kong, Feb 21-23, 2000.